The XBP1 antibody from MyBioSource.com is a Mouse Monoclonal antibody to X-box binding protein 1, XBP-1, XBP1, and XBP2. This antibody recognizes Human antigen. The XBP1 antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Mouse monoclonal XBP1 antibody
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)